Drug Candidates
138
Total Drug Candidates
100K+
From OpenTarget Hits
40
Target Pathways
95%+
Literature Validated
Drug Type Distribution
Protein46.94%
Small Molecule40.38%
Antibody6.4%
Oligonucleotide3.9%
Clinical Phase Distribution
Phase II
57 drugs41.38%
Phase I
42 drugs30.78%
Phase III
28 drugs20.57%
Approved
6 drugs4.56%
Phase 0.5
4 drugs2.72%
Top Drug Candidates
AZD2423
Phase IISmall Molecule18 pathways
12 target genes
No adverse effects
247 PubMed citations
Mechanism: AGONIST
AVACOPAN
ApprovedSmall Molecule14 pathways
8 target genes
3 adverse events
189 PubMed citations
Mechanism: ANTAGONIST
BMS-813160
Phase IIIAntibody11 pathways
6 target genes
1 adverse events
156 PubMed citations
Mechanism: ANTAGONIST
AGATOLIMOD
Phase IIOligonucleotide9 pathways
5 target genes
2 adverse events
134 PubMed citations
Mechanism: AGONIST
Mechanism Distribution
57.02%
AGONIST
39.21%
ANTAGONIST
3.05%
BLOCKER
0.72%
Other